Humatrope (somatropin) is a synthetic human growth hormone used to treat growth failure in children and growth hormone deficiency in adults. Note that Eli Lilly is permanently discontinuing the distribution of Humatrope on December 31, 2026.
- Children: Treats growth hormone deficiency, Turner syndrome, idiopathic short stature, SHOX deficiency, and growth failure in children born small for gestational age.
- Adults: Replaces endogenous growth hormone in adults with confirmed deficiency
- Given as a subcutaneous injection under the skin.
- Delivered using the matching HumatroPen device (available in 6 mg, 12 mg, and 24 mg sizes to match the corresponding medicine cartridges).
- Injected daily (6 to 7 days per week) into rotating sites like the abdomen, thigh, or upper arm.
- Contraindications: Do not use in patients with active cancer, closed growth plates (epiphyses), severe acute critical illness, or specific severe respiratory impairments/Prader-Willi syndrome risks.
- Side Effects: Common reactions include joint/muscle pain, swelling, rapid weight gain, headache, and injection-site pain or itching.




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