Januvia (sitagliptin) is a prescription oral medication used alongside diet and exercise to lower blood sugar levels in adults with type 2 diabetes.
How It Works
- Januvia belongs to the DPP-4 inhibitor (dipeptidyl peptidase-4) class of drugs.
- It blocks the DPP-4 enzyme, which breaks down gut hormones called incretins (GLP-1 and GIP).
- Higher incretin levels increase insulin release after meals and decrease glucose made by the liver.
- It is not for treating type 1 diabetes or diabetic ketoacidosis.
Dosage and Administration
- The standard adult dose is 100 mg taken once daily.
- It can be taken with or without food, at any time of day, but should be taken at the same time consistently.
- Lower doses (such as 25 mg or 50 mg) may be prescribed for people with kidney problems.
Common Side Effects
- Stuffy or runny nose, sore throat
- Headache
- Upper respiratory tract infection
- Upset stomach or diarrhea (when combined with other drugs).
Serious Risks and Warnings
- Pancreatitis: Severe upper stomach pain that radiates to the back.
- Hypoglycemia: Low blood sugar can occur if taken with insulin or sulfonylureas.
- Heart failure: Symptoms include shortness of breath or sudden leg swelling.
- Severe joint or skin reactions: Joint pain or blistering skin rashes (bullous pemphigoid).
| MG | 25 mg 30 tablets, 50 mg 30 tablets, 100 mg 30 tablets |
|---|---|
| Cat. No | Januvia |
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